interleukin 2 การใช้

• Interleukin 2 is a protein that regulates the body's immune response.
• Cetus did not get approval on Interleukin 2, a cancer drug.
• The researchers hope interleukin 2 will translate into better survival rates for AIDS patients.
• It has been shown to increase lymphocyte numbers and Interleukin 2 production in animals.
• This interaction inhibits interleukin 2 transcription in T cells.
• Nuclear factor of activated T-cells ( NFAT ) is a transcription factor required for T-cell expression of interleukin 2.
• NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2.
• The new approach involves on-and-off infusions of interleukin 2 or IL-2, a natural protein that regulates the body's immune defenses.
• The drug, an injectable, recombinant form of interleukin 2, represents $ 100 million of Chiron's $ 1.2 billion annual revenues.
• Interleukin 2 ( IL-2 ) is a protein that helps T cells of the immune system attack pathogens and tumors.
• It is also expressed in T lymphocytes and may function to inhibit interleukin 2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.
• Nuclear factor of activated T-cells ( NFAT ) is a transcription factor required for T-cell expression of the interleukin 2 gene.
• These factors, which include interleukin 2 ( IL2 ), are secreted by lectin-or antigen-stimulated T cells, and have various physiological effects.
• This complex of ciclosporin and cyclophilin inhibits calcineurin, which, under normal circumstances, is responsible for activating the transcription of interleukin 2.
• The drug, an injectable, recombinant form of interleukin 2, represents $ 100 million of Chiron's $ 1 . 2 billion annual revenues.
• The compound works by binding to a receptor for a chemical called interleukin 2, located on the surface of killer immune cells.
• Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2.
• Blockade of K v 1.3 channels in effector-memory T cells suppresses calcium signaling, cytokine production ( interferon-gamma, interleukin 2 ) and cell proliferation.
• Those drugs, like Chiron's Interleukin 2 or Amgen Inc .'s Epogen, are copies of naturally occurring proteins that are manufactured in giant fermentation vats.
• Dr . Izzie Stevens ( Katherine Heigl ) is scheduled for an interleukin 2 ( IL-2 ) treatment but is absent from the hospital.